Vitamin K2 plays a significant role in calcium utilization for optimal bone and heart health because it puts calcium where it is needed – into bones, not arteries. K2’s mechanism of action involves two key proteins - osteocalcin and matrix Gla protein (MGP). Osteocalcin plays a role in the integration of calcium into the bone matrix whereas MGP keeps calcium away from arteries. There’s a strong association exist between decreased bone mineral density and increased risk of both cardiovascular disease (CV) and CV death. Unfortunately, our diets today do not provide us with enough vitamin K2. Therefore, there is a need for K2 supplementation. 
 

In fact, K2 was ‘the missing vitamin’ for a long time. The deficiency of K2 is especially manifested in people who has chronic kidney disease (CKD), dialysis, diabetes, and post-menopausal women. Emerging evidence has suggested that vitamin K together with vitamin D may confer protective effects for both skeletal and CV systems. The perfect pair, Vitamin K2 & D3 work synergistically to support the benefits of calcium for both bone health and lowers the risk of arterial calcification to maintain cardiovascular health.